Disorders of Myelin in the Central and Peripheral Nervous System

This comprehensive reference on the principles and clinical practice of all disorders of myelin provides information on the historical, biological, immunological, and pathophysiological background of a range of disorders, including multiple sclerosis. It also covers all epidemiologic, diagnostic, and management considerations. The newer concepts are emphasized, including the presence of concomitant axonal damage in demyelinating disease, and the need for early clinical intervention. Written by recognized experts, the book also focuses on the outcomes of the latest clinical trials in multiple sclerosis, the use of surrogate disease markers, and the advent of disease-modifying therapies. Written for both general neurologists and specialists, this clinically practical book should appeal to all practitioners involved in the treatment of patients with disorders of myelin.